The genesis of heart surgery.

Genesis and regulation of the heart automaticity.

The heart automaticity is a fundamental physiological function in higher organisms. The spontaneous activity is initiated by specialized populations of cardiac cells generating periodical electrical oscillations. The exact cascade of steps initiating the pacemaker cycle in automatic cells has not yet been entirely elucidated. Nevertheless, ion channels and intracellular Ca(2+) signaling are nec...

Treatment of Open Heart Surgery Complications

This article has no abstract.

Genesis of high frequency heart sounds.

Sir, The recent paper by Trail et al. (Br Heart J 1982; 48: 78-80) provides interesting support for the valvular genesis of high frequency heart sounds. As was shown by Mills et al.,I we were able to record a diastolic heart sound simultaneously with echocardiographc mitral valve closure in a "normal" patient with congenital heart block. The intensity of such sounds, however, never reached the ...

Extrinsic factors in the genesis of congenital heart disease.

The extrinsic factors responsible for the production of congenital heart malformations both clinically and experimentally are reviewed. The method to be followed in the investigation of extrinsic factors as teratogenic agents for the a heart and the great vessels both clinically and experimentally is studied. With Saxen and Rapola's work as a starting point, an hypothesis isproposed on thepatho...

Surgery of the Heart